"By assembling into large structures, the antibiotic plectasin latches onto its target on the bacterial cell surface. This is comparable to how both sides of Velcro form a bond. Credit: Gloria Fuentes, edited" (ScitechDaily, Velcro vs. Bacteria: A New Twist in Antibiotic Warfare)
The miniature Velcro fiber can surround bacteria. "Researchers discovered a novel antibacterial mechanism of plectasin, an antibiotic derived from a fungus. The study reveals that plectasin forms Velcro-like structures that trap crucial bacterial components, preventing their escape and enhancing drug effectiveness. This mechanism could guide the development of new antibiotics to fight antimicrobial resistance".(ScitechDaily, Velcro vs. Bacteria: A New Twist in Antibiotic Warfare)
Those nanotechnical Velcro fibers act like tentacles in cancer cells. Those things pull energy out from other cells. And that makes it hard for immune cells to destroy cancer cells. Those nanotubes pull energy out from immune cells. And the same thing can make bacteria weaker. If bacteria turns weaker there is no need for big antibiotic doses.
The fiber can also carry enzymes and acids. That could break the cell's shell and destroy the bacteria or other non-wanted cells.
Maybe the nanowires and nanotubes are another component for two-component medicines. The medicine can involve two components. The medicine, that destroys bacteria. And the other components. That decreases its energy production.
"Left: Field emission scanning electron microscopy (FESEM) image shows the formation of a nanotube between a breast cancer cell and an immune cell. Right: Confocal microscopy image shows mitochondria (labeled with green fluorescence dye) traveling from a T cell to a cancer cell through the intercellular nanotube. DNA in the mitochondria was labeled with blue dye. Credit: Nature Nanotechnology doi: 10.1038/s41565-021-01000-4" (ScitechDaily, Cancer Cells Use “Tiny Tentacles” To Suck Mitochondria Out of Immune Cells)
The ricin molecules are the base for those fibers. The cell pulls ricin molecules inside it. And then that molecule opens its structure and fills the cell. The fiber-based medicine can be an enzyme that destroys the cell membrane from outside or inside that cell. Nanotubes could also pull mitochondria out of cancer cells.
Cancer cells steal mitochondria from immune cells using nanotubes. So antibiotics or their assistants can pull mitochondria out from bacteria. Same way the cancer cells decrease immune cell's energy production. That decreases bacteria's energy production, and that turns it weaker.
In some versions, the medicine can involve fibers like cellulose. There is the nutrient that will take those fibers to the non-wanted cells. And then those very long fibers pull energy out from the bacteria.
In some other versions, the cellulose fiber could open. And then fill the wanted cells. In fiber-based medicines, the idea is that the targeted cells can pull the fiber in it. And then that fiber denies ion pump closing.
Or it can fill the wanted cell. The idea in those fiber-based medicines is that regular fibers like cellulose or nylon. Those fibers deny the normal actions of the cells by filling them. Or it can take energy out of the cell. And make the ion pumps low voltage. Bacteria cannot turn resistant to those fibers. And that makes them interesting tools for the next-generation medicals.
https://scitechdaily.com/cancer-cells-use-tiny-tentacles-to-suck-mitochondria-out-of-immune-cells/
https://scitechdaily.com/velcro-vs-bacteria-a-new-twist-in-antibiotic-warfare/
https://en.wikipedia.org/wiki/Ricin
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